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PKUMDL-WQ-2101

CAS No. 304481-72-9

PKUMDL-WQ-2101 ( —— )

Catalog No. M27914 CAS No. 304481-72-9

PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with anti-tumor activity, it binds to site I.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PKUMDL-WQ-2101
  • Note
    Research use only, not for human use.
  • Brief Description
    PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with anti-tumor activity, it binds to site I.
  • Description
    PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with anti-tumor activity, it binds to site I.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PDE9A;PDE5A1;PDE1B;PDE4D2;PDE10A1;PDE2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    304481-72-9
  • Formula Weight
    317.3
  • Molecular Formula
    C14H11N3O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)C2=CC=C(O)C=C2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.1. Huang M, Shao Y, Hou J, et al. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol Pharmacol. 2015;88(5):836-845.
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