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PKUMDL-LC-101-D04
CAS No. 2143896-83-5
PKUMDL-LC-101-D04( —— )
Catalog No. M34896 CAS No. 2143896-83-5
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of ferroptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 122 | Get Quote |
|
| 5MG | 275 | Get Quote |
|
| 10MG | 407 | Get Quote |
|
| 25MG | 631 | Get Quote |
|
| 50MG | 891 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 500MG | 2358 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePKUMDL-LC-101-D04
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NoteResearch use only, not for human use.
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Brief DescriptionPKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a regulator of ferroptosis.
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DescriptionPKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGPX
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Research Area——
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Indication——
Chemical Information
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CAS Number2143896-83-5
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Formula Weight378.94
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Molecular FormulaC14H23ClN4O2S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (659.74 mM; Ultrasonic )
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SMILESCl.NCCNS(=O)(=O)c1ccc(NC(=S)NC2CCCC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275. ?
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