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PH-002

CAS No. 1311174-68-1

PH-002 ( —— )

Catalog No. M23470 CAS No. 1311174-68-1

PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells. It also could rescue impairments of mitochondrial motility and neurite outgrowth.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PH-002
  • Note
    Research use only, not for human use.
  • Brief Description
    PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells. It also could rescue impairments of mitochondrial motility and neurite outgrowth.
  • Description
    PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells. It also could rescue impairments of mitochondrial motility and neurite outgrowth.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Apo E4 in FRET
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1311174-68-1
  • Formula Weight
    491.6
  • Molecular Formula
    C27H33N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:75 mg/mL (152.57 mM)
  • SMILES
    CC(C)(C)OC(N1CCN(Cc(cc2)ccc2NC(CC(c2c3cccc2)=NN(C)C3=O)=O)CC1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Brodbeck J, et al. Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors. J Biol Chem. 2011 May 13;286(19):17217-26.
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