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PF9366

CAS No. 72882-78-1

PF9366 ( PF 9366;PF-9366 )

Catalog No. M20081 CAS No. 72882-78-1

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PF9366
  • Note
    Research use only not for human use.
  • Brief Description
    PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
  • Description
    PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
  • Synonyms
    PF 9366;PF-9366
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Mat2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72882-78-1
  • Formula Weight
    350.84
  • Molecular Formula
    C20H19ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 20 mg/mL (57 mM)
  • SMILES
    CN(C)CCc1nnc2cc(-c3ccccc3)c3cc(Cl)ccc3n12
  • Chemical Name
    2-(7-Chloro-5-phenyl-[124]triazolo[43-a]quinolin-1-yl)-NN-dimethylethan-1-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Quinlan CL et al. Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat Chem Biol. 2017 Jul;13(7):785-792.
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