PF9366

CAS No. 72882-78-1

PF9366 ( PF 9366;PF-9366 )

Catalog No. M20081 CAS No. 72882-78-1

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 112 In Stock
10MG 164 In Stock
25MG 247 In Stock
50MG 374 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PF9366
  • Note
    Research use only not for human use.
  • Brief Description
    PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
  • Description
    PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).
  • Synonyms
    PF 9366;PF-9366
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Mat2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72882-78-1
  • Formula Weight
    350.84
  • Molecular Formula
    C20H19ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 20 mg/mL (57 mM)
  • SMILES
    CN(C)CCc1nnc2cc(-c3ccccc3)c3cc(Cl)ccc3n12
  • Chemical Name
    2-(7-Chloro-5-phenyl-[124]triazolo[43-a]quinolin-1-yl)-NN-dimethylethan-1-amine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Quinlan CL et al. Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat Chem Biol. 2017 Jul;13(7):785-792.
molnova catalog
related products
  • Lappaconitine

    Lappaconitine, isolated from Aconitum sinomontanum Nakai, was characterized as analgesic principle.

  • KRN5

    KRN5 has potential to treat NFAT5-mediated Chronic Arthritis. KRN5, a derivative of KRN2, is an oral active Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC50 of 750 nM.

  • Pyridaben

    Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).