PF-543

CAS No. 1415562-82-1

PF-543 ( Sphingosine Kinase 1 Inhibitor II )

Catalog No. M18007 CAS No. 1415562-82-1

PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 In Stock
5MG 70 In Stock
10MG 104 In Stock
25MG 196 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PF-543
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
  • Description
    PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
  • Synonyms
    Sphingosine Kinase 1 Inhibitor II
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SphK1; SphK1
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1415562-82-1
  • Formula Weight
    465.6
  • Molecular Formula
    C27H31NO4S
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    C(O)[C@@H]1N(CCC1)Cc1ccc(cc1)COc1cc(cc(c1)C)CS(=O)(=O)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schnute ME, et al. Biochem J, 2012, 444(1), 79-88.
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