Cart
sales@molnova.com
PF-543
CAS No. 1415562-82-1
PF-543 ( Sphingosine Kinase 1 Inhibitor II )
Catalog No. M18007 CAS No. 1415562-82-1
PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
|
| 5MG | 70 | In Stock |
|
| 10MG | 104 | In Stock |
|
| 25MG | 196 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-543
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
-
DescriptionPF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
-
SynonymsSphingosine Kinase 1 Inhibitor II
-
PathwayOthers
-
TargetOther Targets
-
RecptorSphK1; SphK1
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1415562-82-1
-
Formula Weight465.6
-
Molecular FormulaC27H31NO4S
-
Purity98%
-
Solubility——
-
SMILESC(O)[C@@H]1N(CCC1)Cc1ccc(cc1)COc1cc(cc(c1)C)CS(=O)(=O)c1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schnute ME, et al. Biochem J, 2012, 444(1), 79-88.
molnova catalog
related products
-
Alpidem
Alpidem is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar binding affinity for both the central benzodiaze
-
1-Hydroxy-2,3,4,7-te...
1-Hydroxy-2,3,4,7-tetramethoxy-xanthone has vasodilatory action, it can cause vasodilation in the coronary artery pre-contracted with 1uM 5-hydroxytryptamine (5-HT), with the EC 50 value of 6.6±1.4 uM.
-
(R)-Mucronulatol
The herbs of Lotus corniculatus L.
