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PF-06952229
CAS No. 1801333-55-0
PF-06952229 ( PF06952229 )
Catalog No. M26371 CAS No. 1801333-55-0
PF-06952229 is an selective and orally active inhibitor of TGFbR1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | Get Quote |
|
| 10MG | 447 | Get Quote |
|
| 25MG | 714 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | 1368 | Get Quote |
|
| 500MG | 2673 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePF-06952229
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NoteResearch use only, not for human use.
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Brief DescriptionPF-06952229 is an selective and orally active inhibitor of TGFbR1.
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DescriptionPF-06952229 is an selective and orally active inhibitor of TGFbR1.(In Vivo):In MCF-7 ER+ HER2-xenograft breast cancer tumor model, PF-06952229 (30 mg/kg; gavage) combines with Palbociclib results in an improved inhibition of pSMAD2 and a significant increase in survival.
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SynonymsPF06952229
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PathwayOthers
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TargetOther Targets
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RecptorMRP4; OAT1; OAT3
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Research Area——
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Indication——
Chemical Information
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CAS Number1801333-55-0
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Formula Weight458.9
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Molecular FormulaC23H24ClFN4O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)c1cnc(cc1Nc1ccncc1C(=O)NC(CO)CO)-c1cc(Cl)ccc1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kamiński T, Micha?owska M, Pawlak D. Aryl hydrocarbon receptor (AhR) and its endogenous agonist - indoxyl sulfate in chronic kidney disease. Postepy Hig Med Dosw (Online). 2017 Jul 30;71(0):624-632. Review.
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