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PF-06928215
CAS No. 2378173-15-8
PF-06928215( —— )
Catalog No. M24095 CAS No. 2378173-15-8
PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 170 | In Stock |
|
| 10MG | 250 | In Stock |
|
| 25MG | 475 | In Stock |
|
| 50MG | 692 | In Stock |
|
| 100MG | 972 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-06928215
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NoteResearch use only, not for human use.
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Brief DescriptionPF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
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DescriptionPF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
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In VitroPF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorcGAS
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Research Area——
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Indication——
Chemical Information
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CAS Number2378173-15-8
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Formula Weight380.4
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Molecular FormulaC20H20N4O4
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Purity>98% (HPLC)
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SolubilityDMSO:33.33 mg/mL (87.62 mM; Need ultrasonic)
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SMILESOC1=CC(C2=CC=CC=C2)=NC3=C(C(N[C@H]4CCCC[C@H]4C(O)=O)=O)C=NN13
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hall J, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS One. 2017 Sep 21;12(9):e0184843.
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