PF-06928215 ( —— )

Catalog No. M24095 CAS No. 2378173-15-8

PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

PF-06928215
Note

Research use only, not for human use.
Brief Description

PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
Description

PF-06928215 is an inhibitor of cGAS (cyclic GMP-AMP Synthase) (IC50 of 4.9 μΜ).
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

cGAS
Research Area

——
Indication

——

Chemical Information

CAS Number

2378173-15-8
Formula Weight

380.4
Molecular Formula

C20H20N4O4
Purity

>98% (HPLC)
Solubility

DMSO:33.33 mg/mL (87.62 mM; Need ultrasonic)
SMILES

OC1=CC(C2=CC=CC=C2)=NC3=C(C(N[C@H]4CCCC[C@H]4C(O)=O)=O)C=NN13
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hall J, et al. Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS One. 2017 Sep 21;12(9):e0184843.

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