PF-05221304

CAS No. 1370448-25-1

PF-05221304( NSC 170984, R 6238, STAT5 Inhibitor III )

Catalog No. M23101 CAS No. 1370448-25-1

PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first committed step in de novo lipogenesis (DNL).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 264 In Stock
10MG 397 In Stock
25MG 690 In Stock
50MG 896 In Stock
100MG 1305 In Stock
200MG 1755 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PF-05221304
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first committed step in de novo lipogenesis (DNL).
  • Description
    PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first committed step in de novo lipogenesis (DNL).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 170984, R 6238, STAT5 Inhibitor III
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1370448-25-1
  • Formula Weight
    502.57
  • Molecular Formula
    C28H30N4O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)N1C2=C(CC3(CCN(C(C4=CC(C5=CC=C(C(O)=O)C=C5)=NC(OC)=C4)=O)CC3)CC2=O)C=N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • Camellianin A

    Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the significant increase of the G0/G1 cell population.

  • Saikosaponin B1

    Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.

  • Hecogenin

    Hecogenin is a steroid saponin isolated from Agave sisalana. It is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities including anti-inflammatory antifungal and gastroprotective effects.