PF-05212377 ( SAM-760;PF 5212377 )

Catalog No. M10869 CAS No. 1226793-34-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

PF-05212377
Note

Research use only, not for human use.
Brief Description

PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.
Description

PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
Synonyms

SAM-760;PF 5212377
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Neurological Disease
Indication

Alzheimer Disease

CAS Number

1226793-34-5
Formula Weight

356.44
Molecular Formula

C18H20N4O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole

1. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.
2. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.

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