PF-04937319

CAS No. 1245603-92-2

PF-04937319 ( —— )

Catalog No. M26783 CAS No. 1245603-92-2

PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 48 Get Quote
5MG 80 Get Quote
10MG 140 Get Quote
25MG 290 Get Quote
50MG 528 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PF-04937319
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.
  • Description
    PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    AMPK; EGFR; Fatty Acid Synthase (FASN); PGE; PTK; Src
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1245603-92-2
  • Formula Weight
    432.4
  • Molecular Formula
    C22H20N6O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C)C(=O)c1ncc(Oc2cc(cc3oc(C)cc23)C(=O)Nc2cnc(C)cn2)cn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vukic MD, et al. Antibacterial and cytotoxic activities of naphthoquinone pigments from Onosma visianii Clem. EXCLI J. 2017 Feb 16;16:73-88.
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