PF-03814735

CAS No. 942487-16-3

PF-03814735 ( —— )

Catalog No. M17679 CAS No. 942487-16-3

PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PF-03814735
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
  • Description
    PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Aurora A; Aurora B;FLT1 ;FAK; TrkA
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    942487-16-3
  • Formula Weight
    474.48
  • Molecular Formula
    C23H25F3N6O2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 47 mg/mL; 99.06 mM
  • SMILES
    CC(=O)NCC(=O)N1[C@H]2CC[C@@H]1C3=C2C=CC(=C3)NC4=NC=C(C(=N4)NC5CCC5)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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