Cart
sales@molnova.com
PF-01247324
CAS No. 875051-72-2
PF-01247324 ( PF-01247324; PF 01247324; PF01247324 )
Catalog No. M19208 CAS No. 875051-72-2
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 60 | In Stock |
|
| 10MG | 101 | In Stock |
|
| 25MG | 219 | In Stock |
|
| 50MG | 402 | In Stock |
|
| 100MG | 606 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-01247324
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
-
DescriptionPF-01247324 is a novel selective and orally bioavailable Nav 1.8 channel blocker, attenuates nociception and sensory neuron excitability.
-
SynonymsPF-01247324; PF 01247324; PF01247324
-
PathwayOthers
-
TargetOther Targets
-
RecptorNa(V1.8) channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number875051-72-2
-
Formula Weight330.6
-
Molecular FormulaC13H10Cl3N3O
-
Purity98%
-
SolubilityDMSO : ≥ 30 mg/mL; 90.74 mM
-
SMILESCNC(=O)c1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl
-
Chemical Name6-amino-N-methyl-5-(2,3,5-trichlorophenyl)pyridine-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Payne CE, et al. A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability. Br J Pharmacol. 2015 May;172(10):2654-70.
molnova catalog
related products
-
Acid-C1-PEG5-Boc
Acid-C1-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
JK-P3
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
-
13-Dimethyl-5-(2-pro...
13-Dimethyl-5-(2-propen-1-yl)-246(1H3H5H)-pyrimidinetrione is a reagent of research interest in the study alkene cyclization.
