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PF-00489791
CAS No. 853003-48-2
PF-00489791( —— )
Catalog No. M34372 CAS No. 853003-48-2
PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 160 | Get Quote |
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| 5MG | 217 | Get Quote |
|
| 10MG | 330 | Get Quote |
|
| 25MG | 532 | Get Quote |
|
| 50MG | 759 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePF-00489791
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NoteResearch use only, not for human use.
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Brief DescriptionPF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.
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DescriptionPF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1.5 nM. PF-00489791 can enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research Area——
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Indication——
Chemical Information
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CAS Number853003-48-2
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Formula Weight476.55
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Molecular FormulaC20H28N8O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NS(C)(=O)=O)(=O)C=1C=2C(=C(NC3=CC(C)=CC=N3)N=C(N(CC)C)N2)N(CCOCC)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Frank S Menniti, et al. A non-brain penetrant PDE5A inhibitor improves functional recovery after stroke in rats. Restor Neurol Neurosci. 2012;30(4):283-9.?
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