PDE9-IN-1

CAS No. 2305087-92-5

PDE9-IN-1 ( —— )

Catalog No. M26362 CAS No. 2305087-92-5

PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 205 Get Quote
10MG 320 Get Quote
25MG 531 Get Quote
50MG 773 Get Quote
100MG 1062 Get Quote
500MG 2133 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PDE9-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).
  • Description
    PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).(In Vivo):In the Unilateral common carotid artery occlusion (UCCAO) mouse model, PDE9-IN-1 (2.5-5.0 mg/kg; orally) significantly reduces the day 6 escape latency time, increases the frequency of platform area crossings, and recoveres learning and memory function. High dose group possibly improved the escape latency time of mice.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NMDA receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2305087-92-5
  • Formula Weight
    362.4
  • Molecular Formula
    C17H23FN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@@H](Nc1nc2n(ncc2c(=O)[nH]1)C1CCCC1)C(=O)N1CC[C@H](F)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lozovaya N, Gataullina S, et al. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat Commun. 2014 Aug 1;5:4563.
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