PDE9-IN-1

Research use only, not for human use.

PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).

PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).(In Vivo):In the Unilateral common carotid artery occlusion (UCCAO) mouse model, PDE9-IN-1 (2.5-5.0 mg/kg; orally) significantly reduces the day 6 escape latency time, increases the frequency of platform area crossings, and recoveres learning and memory function. High dose group possibly improved the escape latency time of mice.

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Others

Other Targets

NMDA receptor

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2305087-92-5

362.4

C17H23FN6O2

>98% (HPLC)

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C[C@@H](Nc1nc2n(ncc2c(=O)[nH]1)C1CCCC1)C(=O)N1CC[C@H](F)C1

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(-20℃)

With Ice Pack

≥ 2 years