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PDE9-IN-1
CAS No. 2305087-92-5
PDE9-IN-1 ( —— )
Catalog No. M26362 CAS No. 2305087-92-5
PDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | Get Quote |
|
| 10MG | 320 | Get Quote |
|
| 25MG | 531 | Get Quote |
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| 50MG | 773 | Get Quote |
|
| 100MG | 1062 | Get Quote |
|
| 500MG | 2133 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePDE9-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionPDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).
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DescriptionPDE9-IN-1 is a potent, selective, and orally bioavailable Inhibitor of phosphodiesterase-9A (PDE9A)(IC50 of 8.7 nM).(In Vivo):In the Unilateral common carotid artery occlusion (UCCAO) mouse model, PDE9-IN-1 (2.5-5.0 mg/kg; orally) significantly reduces the day 6 escape latency time, increases the frequency of platform area crossings, and recoveres learning and memory function. High dose group possibly improved the escape latency time of mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorNMDA receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2305087-92-5
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Formula Weight362.4
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Molecular FormulaC17H23FN6O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@@H](Nc1nc2n(ncc2c(=O)[nH]1)C1CCCC1)C(=O)N1CC[C@H](F)C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lozovaya N, Gataullina S, et al. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat Commun. 2014 Aug 1;5:4563.
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