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PD-L1-IN-3
CAS No. 2953044-29-4
PD-L1-IN-3( —— )
Catalog No. M37233 CAS No. 2953044-29-4
PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 137 | Get Quote |
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| 5MG | 211 | Get Quote |
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| 10MG | 337 | Get Quote |
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| 25MG | 634 | Get Quote |
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| 50MG | 1003 | Get Quote |
|
| 100MG | 1557 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePD-L1-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionPD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation.
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DescriptionPD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetPD-1/PD-L1
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RecptorPD-1/PD-L1
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Research Area——
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Indication——
Chemical Information
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CAS Number2953044-29-4
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Formula Weight373.85
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Molecular FormulaC19H15ClFN2OS
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Purity>98% (HPLC)
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Solubility——
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SMILES[Cl].N#CC1=C(OCC2=CC=C(C=C2)CN)SC=C1C=3C=CC(F)=CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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