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PD-166866
CAS No. 192705-79-6
PD-166866( PD166866 | PD166866 | PD 166866 )
Catalog No. M17405 CAS No. 192705-79-6
PD166866 is a selective FGFR tyrosine kinase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 50 | In Stock |
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| 10MG | 78 | In Stock |
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| 25MG | 146 | In Stock |
|
| 50MG | 289 | In Stock |
|
| 100MG | 429 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePD-166866
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NoteResearch use only, not for human use.
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Brief DescriptionPD166866 is a selective FGFR tyrosine kinase inhibitor.
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DescriptionPD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD166866 has clear antiproliferative effects.
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In Vitro——
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In Vivo——
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SynonymsPD166866 | PD166866 | PD 166866
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PathwayMembrane Transporter/Ion Channel
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TargetOCT
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RecptorFGFR1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number192705-79-6
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Formula Weight396.45
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Molecular FormulaC20H24N6O3
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Purity>98% (HPLC)
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SolubilityDMSO : 10.33 mg/mL. 26.06 mM;
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SMILESCOc1cc(OC)cc(c1)-c1cc2cnc(N)nc2nc1NC(=O)NC(C)(C)C
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Chemical Name1-(2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Panek RL, et al. In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase. J Pharmacol Exp Ther. 1998 Jul;286(1):569-77.
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PD-166866
PD166866 is a selective FGFR tyrosine kinase inhibitor.
