PD-161570
CAS No. 192705-80-9
PD-161570 ( PD 161570; PD-161570 )
Catalog No. M27679 CAS No. 192705-80-9
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 124 | Get Quote |
|
5MG | 200 | Get Quote |
|
10MG | 295 | Get Quote |
|
25MG | 498 | Get Quote |
|
50MG | 710 | Get Quote |
|
100MG | 963 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePD-161570
-
NoteResearch use only, not for human use.
-
Brief DescriptionPD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
-
DescriptionPD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
-
SynonymsPD 161570; PD-161570
-
PathwayAngiogenesis
-
TargetEGFR
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number192705-80-9
-
Formula Weight532.5
-
Molecular FormulaC26H35Cl2N7O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Eilender D, et al. 4,4'-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007): a topical treatment for cutaneous metastases from malignant cancers. Cancer Chemother Pharmacol. 2006 Jun;57(6):719-26.
molnova catalog
related products
-
Poziotinib
Poziotinib (HM781-36B, NOV120101) is an irreversible pan-HER inhibitor with IC50 of 3.2/5.3 nM/23.5 nM for HER1/HER2/HER4.
-
CP-724714
CP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM.
-
AZ5104
AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor.