Cart
sales@molnova.com
Home - Products - Proteasome/Ubiquitin - Proteasome - PD-151746

PD-151746

CAS No. 179461-52-0

PD-151746( PD151746 | PD-151746 )

Catalog No. M12706 CAS No. 179461-52-0

A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 In Stock
10MG 88 In Stock
25MG 178 In Stock
50MG 285 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    PD-151746
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain.
  • Description
    A potent, selective, cell-permeable Calpain inhibitor with Ki of 0.26 uM for m-calpain; displays 20-fold selectivity over m-calpain; attenuates the SLLVY-AMC hydrolysis induced by maitotoxin in SY5Y cells; decreases cytotoxicity induced by oxidized low-density lipoprotein (oxLDL) in HMEC-1 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PD151746 | PD-151746
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Proteasome
  • Recptor
    m-calpain|μ-Calpain
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    179461-52-0
  • Formula Weight
    237.2501
  • Molecular Formula
    C11H8FNO2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 37 mg/mL
  • SMILES
    O=C(O)/C(S)=C/C1=CNC2=C1C=C(F)C=C2
  • Chemical Name
    2-Propenoic acid, 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang KK, et al. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92. 2. Porn-Ares MI, et al. Biochem J. 2003 Sep 1;374(Pt 2):403-11.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Linagliptin Methyldi...

    Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.

  • RA375

    RA375, an inhibitor of RPN13 (26S proteasome regulatory subunit), enhances UPR signaling, ROS production, and apoptosis.

  • PSI

    PSI is a proteasome inhibitor.

Sign In Join Free