PD-1-IN-22 ( —— )

Catalog No. M26359 CAS No. 2349372-98-9

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

PD-1-IN-22
Note

Research use only, not for human use.
Brief Description

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
Description

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).(In Vitro):PD-1-IN-22 dose-dependently elevates interferon-γ（IFN-γ) secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

DGK
Research Area

——
Indication

——

Chemical Information

CAS Number

2349372-98-9
Formula Weight

459.5
Molecular Formula

C25H25N5O4
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1c(NC(=O)c2cc(CNCCO)cn3cnnc23)cccc1-c1ccc2OCCOc2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Slack BE, Richardson UI, Nitsch RM, Wurtman RJ. Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. Brain Res. 1992 Jul 10;585(1-2):169-76.

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