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PD-1-IN-22

CAS No. 2349372-98-9

PD-1-IN-22( —— )

Catalog No. M26359 CAS No. 2349372-98-9

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PD-1-IN-22
  • Note
    Research use only, not for human use.
  • Brief Description
    PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
  • Description
    PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).(In Vitro):PD-1-IN-22 dose-dependently elevates interferon-γ（IFN-γ) secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.
  • In Vitro
    PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DGK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2349372-98-9
  • Formula Weight
    459.506
  • Molecular Formula
    C25H25N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1c(NC(=O)c2cc(CNCCO)cn3cnnc23)cccc1-c1ccc2OCCOc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Slack BE, Richardson UI, Nitsch RM, Wurtman RJ. Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line. Brain Res. 1992 Jul 10;585(1-2):169-76.
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