PCI-34051

CAS No. 950762-95-5

PCI-34051 ( PCI34051; PCI 34051; PCI-34051 )

Catalog No. M16799 CAS No. 950762-95-5

PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 50 In Stock
10MG 87 In Stock
25MG 176 In Stock
50MG 335 In Stock
100MG 537 In Stock
500MG 1134 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PCI-34051
  • Note
    Research use only, not for human use.
  • Brief Description
    PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.
  • Description
    PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10.
  • Synonyms
    PCI34051; PCI 34051; PCI-34051
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC1; HDAC10; HDAC2; HDAC6; HDAC8
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    950762-95-5
  • Formula Weight
    296.32
  • Molecular Formula
    C17H16N2O3
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO:59 mg/mL (199.1 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
  • SMILES
    O=C(C1=CC2=C(C=C1)C=CN2CC3=CC=C(OC)C=C3)NO
  • Chemical Name
    N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Balasubramanian S, et al. Leukemia. 2008, 22(5), 1026-1034.
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