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PALDA
CAS No. 136181-87-8
PALDA( —— )
Catalog No. M33899 CAS No. 136181-87-8
PALDA (N-Palmitoyl dopamine) is a fatty acid dopamine found in the mammalian brain that is inactive against TRPV1 and inactivates at TRPV(1)R. It is used in the study of duodenal ulcers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 61 | Get Quote |
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| 5MG | 87 | Get Quote |
|
| 10MG | 128 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePALDA
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NoteResearch use only, not for human use.
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Brief DescriptionPALDA (N-Palmitoyl dopamine) is a fatty acid dopamine found in the mammalian brain that is inactive against TRPV1 and inactivates at TRPV(1)R. It is used in the study of duodenal ulcers.
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DescriptionN-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide.
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In VitroPALDA (0.1-10 μM), the EC50 of N-arachidonoyl-dopamine (NADA) is lowered from approximately 90 to approximately 30 nM. The effect on intracellular Ca2+ by another endovanilloid, N-arachidonoyl-ethanolamine (anandamide, 50 nM), is also enhanced dose-dependently by PALDA. PALDA also acted in synergy with low pH (6.0-6.7) to enhance intracellular Ca2+ via TRPV1.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number136181-87-8
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Formula Weight391.59
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Molecular FormulaC24H41NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCCC1=CC=C(O)C(O)=C1)CCCCCCCCCCCCCCC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Luciano De Petrocellis, et al. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. Br J Pharmacol. 2004 Sep;143(2):251-6.?
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