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PAC1
CAS No. 315183-21-2
PAC1 ( Procaspase-activating Compound 1 )
Catalog No. M14020 CAS No. 315183-21-2
PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
|
| 10MG | 39 | In Stock |
|
| 25MG | 68 | In Stock |
|
| 50MG | 113 | In Stock |
|
| 100MG | 203 | In Stock |
|
| 500MG | 822 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePAC1
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NoteResearch use only, not for human use.
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Brief DescriptionPAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
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DescriptionPAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
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SynonymsProcaspase-activating Compound 1
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PathwayApoptosis
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TargetCaspase
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RecptorProcaspase-3
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number315183-21-2
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Formula Weight392.49
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Molecular FormulaC23H28N4O2
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Purity>98%(HPLC)
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SolubilityEthanol: 16 mg/mL (40.76 mM); DMSO: 78 mg/mL (198.73 mM)
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SMILESO=C(N/N=C/C1=CC=CC(CC=C)=C1O)CN2CCN(CC3=CC=CC=C3)CC2
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Chemical Name(E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Putt KS, et al. nat Chem Biol, 2006, 2(10), 543-550.
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