PA-824
CAS No. 187235-37-6
PA-824 ( PA824;PA 824;Pretomanid;(S)-PA 824 )
Catalog No. M12898 CAS No. 187235-37-6
A anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 37 | In Stock |
|
10MG | 59 | In Stock |
|
25MG | 86 | In Stock |
|
50MG | 112 | In Stock |
|
100MG | 172 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePA-824
-
NoteResearch use only, not for human use.
-
Brief DescriptionA anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL).
-
DescriptionA anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL); shows potent bactericidal activity against MDR M. tuberculosis and promising oral activity in animal infection models.
-
SynonymsPA824;PA 824;Pretomanid;(S)-PA 824
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
Recptortuberculosis
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number187235-37-6
-
Formula Weight359.26
-
Molecular FormulaC14H12F3N3O5
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 33 mg/mL
-
SMILESFC(F)(F)OC1=CC=C(C=C1)CO[C@H]2CN3C(OC2)=NC([N+]([O-])=O)=C3
-
Chemical Name5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-, (6S)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Stover CK, et al. Nature. 2000 Jun 22;405(6789):962-6.
2. Tyagi S, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2289-93.
3. Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301.
2. Tyagi S, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2289-93.
3. Lenaerts AJ, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301.
molnova catalog
related products
-
Gatifloxacin
A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
-
XF-73
XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL).
-
Norvancomycin hydroc...
An antibiotic used to treat a number of bacterial infections that acts by inhibiting proper cell wall synthesis.