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P516-0475
CAS No. 1359627-33-0
P516-0475 ( P516-0475; P5160475; P516 0475 )
Catalog No. M11475 CAS No. 1359627-33-0
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).
Purity : >98% (HPLC)
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Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
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50MG | 1782 | Get Quote |
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100MG | 2250 | Get Quote |
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200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameP516-0475
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NoteResearch use only, not for human use.
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Brief DescriptionP516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).
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DescriptionP516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM); specifically induces expression of Rgg2/3-regulated genes in the presence of SHP pheromones at concentrations lower than typically required for QS induction; P516-0475 directly inhibits recombinant PepO in vitro as an uncompetitive inhibitor, induces QS by stabilizing SHP pheromones in culture.
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SynonymsP516-0475; P5160475; P516 0475
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1359627-33-0
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Formula Weight315.33
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Molecular FormulaC15H17N5O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=C2N(N=N1)C3=C(C=C(C)C=C3)NC2=O)NCCCOC
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Chemical NameN-(3-methoxypropyl)-7-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxaline-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pérez Morales TG, et al. J Biol Chem. 2018 Jan 19;293(3):931-940.
molnova catalog
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