Cart
sales@molnova.com
P516-0475
CAS No. 1359627-33-0
P516-0475( P516-0475 | P5160475 | P516 0475 )
Catalog No. M11475 CAS No. 1359627-33-0
P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameP516-0475
-
NoteResearch use only, not for human use.
-
Brief DescriptionP516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM).
-
DescriptionP516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO (IC50=10 uM); specifically induces expression of Rgg2/3-regulated genes in the presence of SHP pheromones at concentrations lower than typically required for QS induction; P516-0475 directly inhibits recombinant PepO in vitro as an uncompetitive inhibitor, induces QS by stabilizing SHP pheromones in culture.
-
In Vitro——
-
In Vivo——
-
SynonymsP516-0475 | P5160475 | P516 0475
-
PathwayGPCR/G Protein
-
TargetAntibacterial
-
RecptorAntibacterial
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1359627-33-0
-
Formula Weight315.333
-
Molecular FormulaC15H17N5O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=C2N(N=N1)C3=C(C=C(C)C=C3)NC2=O)NCCCOC
-
Chemical NameN-(3-methoxypropyl)-7-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxaline-3-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Pérez Morales TG, et al. J Biol Chem. 2018 Jan 19;293(3):931-940.
molnova catalog
related products
-
6-Amino-5-azacytidin...
6-Amino-5-azacytidine has an inhibitory of the growth of E. coli.
-
Sarecycline hydrochl...
Sarecycline hydrochloride (Sarecycline HCl) is an orally active narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity, inhibits Acinetobacter and Candida tropicalis, and can be used to treat inflammatory acne.
-
Mecillinam
Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
