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Oxatomide

CAS No. 60607-34-3

Oxatomide( —— )

Catalog No. M33637 CAS No. 60607-34-3

Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.

Purity : >98% (HPLC)

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HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	49	In Stock
5MG	69	In Stock
10MG	117	In Stock
25MG	227	In Stock
50MG	364	In Stock
100MG	557	In Stock
500MG	1152	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Oxatomide
Note

Research use only, not for human use.
Brief Description

Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.
Description

Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.
In Vitro

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In Vivo

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Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor | Calcium Channel | P2X Receptor | Histamine Receptor
Research Area

——
Indication

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Chemical Information

CAS Number

60607-34-3
Formula Weight

426.55
Molecular Formula

C27H30N4O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (586.10 mM; Ultrasonic )
SMILES

O=C1NC2=C(C=CC=C2)N1CCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kazuki Yoshida, et al. P2X7 receptor antagonist activity of the anti-allergic agent oxatomide. Eur J Pharmacol. 2015 Nov 15;767:41-51.?

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