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Osunprotafib
CAS No. 2489404-97-7
Osunprotafib( —— )
Catalog No. M35583 CAS No. 2489404-97-7
Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 692 | Get Quote |
|
| 5MG | 1292 | Get Quote |
|
| 10MG | 2043 | Get Quote |
|
| 25MG | 3432 | Get Quote |
|
| 50MG | 4536 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameOsunprotafib
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NoteResearch use only, not for human use.
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Brief DescriptionOsunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors.
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DescriptionOsunprotafib (ABBV-CLS-484) is a potent PTPN1 and PTPN2 inhibitor with subnanomolar activity. Osunprotafib has antitumor activity, enhances the immune response and increases the sensitivity of tumors to immune-mediated killing.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorPhosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number2489404-97-7
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Formula Weight385.45
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Molecular FormulaC17H24FN3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (162.15 mM; Ultrasonic )
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SMILESCC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Philip R. Kym, et al. Protein tyrosine phosphatase inhibitors and methods of use thereof. WO2022056281A1.
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