Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - GlyT - Opiranserin

Opiranserin

CAS No. 1441000-45-8

Opiranserin( VVZ-149 | VVZ-000149 )

Catalog No. M11871 CAS No. 1441000-45-8

Opiranserin (VVZ-149, VVZ-000149) is a?potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Opiranserin
  • Note
    Research use only, not for human use.
  • Brief Description
    Opiranserin (VVZ-149, VVZ-000149) is a?potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM).
  • Description
    Opiranserin (VVZ-149, VVZ-000149) is a?potent, selective, mixed glycine GlyT2 transporter blocker (IC50= 0.86 uM), purine P2X3 receptor antagonist (IC50=0.87 uM) and serotonin 5-HT2A receptor antagonist (IC50=1.3 uM); demonstrates analgesic efficacy for postoperative pain.Pain Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VVZ-149 | VVZ-000149
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GlyT
  • Recptor
    GlyT
  • Research Area
    Neurological Disease
  • Indication
    Pain

Chemical Information

  • CAS Number
    1441000-45-8
  • Formula Weight
    394.512
  • Molecular Formula
    C21H34N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NCC1(N(C)C)CCOCC1)C2=CC(OC)=C(OCCCC)C(OC)=C2
  • Chemical Name
    Benzamide, 4-butoxy-N-[[4-(dimethylamino)tetrahydro-2H-pyran-4-yl]methyl]-3,5-dimethoxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nedeljkovic SS, et al. BMJ Open. 2017 Feb 17;7(2):e011035. 2. Oh J, et al. J Clin Pharmacol. 2018 Jan;58(1):64-73.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • LY2365109 hydrochlor...

    LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.

  • ALX-5407 hydrochlori...

    ALX-5407 is a potent, selective, orally active inhibitor of GlyT1 glycine transporter with IC50 of 3 nM.

  • AMG 747

    A nanomolar potent, selective, and orally bioavailable glycine transporter type-1 (GlyT1) inhibitor for the treatment of negative symptoms associated with schizophrenia.

Sign In Join Free