Opicapone ( BIA 9-1067 )

Catalog No. M24972 CAS No. 923287-50-7

Opicapone reduces the ATP content of the cells (IC50: 98 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Opicapone
Note

Research use only, not for human use.
Brief Description

Opicapone reduces the ATP content of the cells (IC50: 98 μM).
Description

Opicapone reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations.
Synonyms

BIA 9-1067
Pathway

Metabolic Enzyme/Protease
Target

Transferase
Recptor

COMT
Research Area

——
Indication

——

Chemical Information

CAS Number

923287-50-7
Formula Weight

413.2
Molecular Formula

C15H10Cl2N4O6
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (242.03 mM; Need ultrasonic)
SMILES

OC1=CC(C2=NC(C3=C(Cl)[N+]([O-])=C(C)C(Cl)=C3C)=NO2)=CC([N+]([O-])=O)=C1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Bonifácio MJ, et al. Pharmacological profile of Opicapone, a third-generation nitrocatechol catechol-O-methyl transferase inhibitor, in the rat. Br J Pharmacol. 2015 Apr;172(7):1739-52.

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