OSMI-4( —— )

Catalog No. M33049 CAS No. 2260791-14-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

OSMI-4
Note

Research use only, not for human use.
Brief Description

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor (EC50 of 3 μM in cells) that can be used to study OGT inhibition in different human cell lines.
Description

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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CAS Number

2260791-14-6
Formula Weight

604.09
Molecular Formula

C27H26ClN3O7S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (103.46 mM; Ultrasonic )
SMILES

CCOC(=O)CN(Cc1cccs1)C(=O)[C@H](NS(=O)(=O)c1cc2ccc(=O)[nH]c2cc1Cl)c1ccccc1OC
Chemical Name

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1. Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.?

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