OSMI-1 ( —— )

Catalog No. M23755 CAS No. 1681056-61-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

OSMI-1
Note

Research use only, not for human use.
Brief Description

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
Description

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor (IC50: 2.7 μM).
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

O-GlcNAc transferase (OGT)
Research Area

——
Indication

——

CAS Number

1681056-61-0
Formula Weight

563.6
Molecular Formula

C28H25N3O6S2
Purity

>98% (HPLC)
Solubility

DMSO:83.33 mg/mL?(147.84 mM;?Need ultrasonic)
SMILES

O=C(N(CC1=CC=CS1)CC2=CC=CO2)[C@H](NS(C3=CC(C=C4)=C(C=C3)NC4=O)(=O)=O)C5=CC=CC=C5OC
Chemical Name

——

1.Ortiz-Meoz RF, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.

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