OSBPL7-IN-1
CAS No. 1269826-44-9
OSBPL7-IN-1 ( —— )
Catalog No. M28764 CAS No. 1269826-44-9
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 222 | Get Quote |
|
10MG | 357 | Get Quote |
|
25MG | 597 | Get Quote |
|
50MG | 851 | Get Quote |
|
100MG | 1152 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameOSBPL7-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionOSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.
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DescriptionOSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression.(In Vitro):OSBPL7-IN-1 (compound G; 1-10?μM) increase plasma membrane ATP-binding cassette transporter (ABCA1) in cultured human podocytes, and significantly increase ABCA1-dependent cholesterol efflux.(In Vivo):OSBPL7-IN-1 (100?mg/kg; oral gavage; daily; for 28 days) treatment normalizes proteinuria, and prevents renal function decline in mouse models of proteinuric kidney disease.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1269826-44-9
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Formula Weight463.3
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Molecular FormulaC20H19Cl2F3N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO[C@H](CCCC1)[C@@H]1NC(c(cn1)cc(-c(cc2)cc(Cl)c2Cl)c1OCC(F)(F)F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Atta-Ur-Rahman, Shabbir M, Khan AM, Hayat S, Nasreen A, Malik S, Choudhary MI. (1999) Chemical constituents from marine organisms. Natural Product Letters, 13, 255-261.
molnova catalog
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