ONC1-13B

CAS No. 1351185-54-0

ONC1-13B( —— )

Catalog No. M34358 CAS No. 1351185-54-0

ONC1-13B is a potent androgen receptor (AR) antagonist with an ic50 in the range of 59-80 nM that inhibits PSA production in androgen-sensitive human PCa LNCaP cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 445 Get Quote
5MG 683 Get Quote
10MG 938 Get Quote
25MG 1371 Get Quote
50MG 1822 Get Quote
100MG 2475 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ONC1-13B
  • Note
    Research use only, not for human use.
  • Brief Description
    ONC1-13B is a potent androgen receptor (AR) antagonist with an ic50 in the range of 59-80 nM that inhibits PSA production in androgen-sensitive human PCa LNCaP cells.
  • Description
    ONC1-13B is a potent androgen receptor (AR) antagonist with an ic50 in the range of 59-80 nM that inhibits PSA production in androgen-sensitive human PCa LNCaP cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1351185-54-0
  • Formula Weight
    492.45
  • Molecular Formula
    C22H16F4N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1[C@@]2(N(C(=S)N1C3=CC(C(F)(F)F)=C(C#N)C=C3)C4=CC(F)=C(C(NC)=O)C=C4)CCOC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • EPI-001

    EPI-001 is a small molecule that blocks transactivation of the androgen Receptor (AR) NTD (IC50=6 uM).

  • AR antagonist 1

    AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.

  • BMS-986365

    BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.