ON-013100

Research use only, not for human use.

ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.

ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.(In Vitro):ON 013100 inhibits the proliferation of MCL (JEKO-1 and MINO), breast (MCF7 and MDA-MB-231), gastric (AGS), and esophageal (OE19, OE33, and FLO-1) cancer cell lines at a nanomolar concentration (ON 013100 GI50=6.7-11.2 nM). ON013100 significantly alters the cell cycle profile, dramatically increasing the number of cells in the G2/M phase. Treatment of the cells with even 0.1 μM of ON013100 results in an arrest of the G2/M phase of the cell cycle. ON-013100 induces apoptosis and has activity against most human cancer cell lines in vitro.

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Angiogenesis

CDK

Sweet taste receptor

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865783-95-5

394.4

C19H22O7S

>98% (HPLC)

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COc1cc(OC)c(\C=C\S(=O)(=O)Cc2ccc(OC)c(O)c2)c(OC)c1

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(-20℃)

With Ice Pack

≥ 2 years