Nortadalafil ( Demethyl Tadalafil )

Catalog No. M20552 CAS No. 171596-36-4

Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	40	In Stock
5MG	65	In Stock
10MG	102	In Stock
25MG	192	In Stock
50MG	335	In Stock
100MG	537	In Stock
200MG	762	In Stock
500MG	1134	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Nortadalafil
Note

Research use only not for human use.
Brief Description

Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
Description

Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
Synonyms

Demethyl Tadalafil
Pathway

Angiogenesis
Target

PDE
Recptor

PDE5
Research Area

——
Indication

——

Chemical Information

CAS Number

171596-36-4
Formula Weight

375.38
Molecular Formula

C21H16N3O4
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL (133.20 mM)
SMILES

O=C1CNC(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Takahiro R Nakamura S Kohno H et al. Contribution of CYP3A Isoforms to Dealkylation of PDE5 Inhibitors: A Comparison between Sildenafil N-Demethylation and Tadalafil Demethylenation[J]. Biological & Pharmaceutical Bulletin 2015 38(1):58-65.

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