Norswertianolin

CAS No. 54954-12-0

Norswertianolin( —— )

Catalog No. M32238 CAS No. 54954-12-0

Norswertianolin, a compound isolated from G. acuta, functions as a CSE activator and shows promise as a potential cardiovascular therapeutic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Norswertianolin
  • Note
    Research use only, not for human use.
  • Brief Description
    Norswertianolin, a compound isolated from G. acuta, functions as a CSE activator and shows promise as a potential cardiovascular therapeutic.
  • Description
    Norswertianolin, a compound isolated from G. acuta, functions as a CSE activator and shows promise as a potential cardiovascular therapeutic.
  • In Vitro
    Norswertianolin (3.125~50 μM; H9c2 cells) has the protective effects on H2O2-induced H9c2 cells. Norswertianolin significantly increases the transcription levels of HO-1 and GCLC in H9c2 cells. Norswertianolin (0~150 μM; HepG2 cells) high concentration increases the CSE protein level.
  • In Vivo
    Norswertianolin (4.4 mg/kg/day; s.c.; 1 week) improves CSE/H2S production.Norswertianolin treatment attenuates the renal tubular injury in acute I/R. Norswertianolin also reduces I/R-stimulated ROS by DHE fluorescence intensity. Norswertianolin has anti-hypertension effects, inhibits vascular remodeling and reduces inflammation effects. Animal Model:Male Sprague Dawley rats (10~12 weeks ) Dosage:4.4 mg/kg/day Administration:S.c.Result:Improved CSE/H2S production.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54954-12-0
  • Formula Weight
    422.34
  • Molecular Formula
    C19H18O11
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (59.19 mM)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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