Nirmatrelvir

Research use only, not for human use.

PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .

PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .(In Vitro):PF-07321332 is a promising oral antiviral clinical candidate with well-established anti-SARS-CoV-2 activity in vitro.(In Vitro):3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.1. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.

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PF-07321332

Others

Other Targets

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2628280-40-8

499.53

C23H32F3N5O4

>98% (HPLC)

In Vitro:?DMSO : 140 mg/mL (280.26 mM)

CC(C)(C)[C@@H](C(N(C[C@@H]1C(C)(C)[C@H]11)[C@@H]1C(N[C@@H](C[C@H](CCN1)C1=O)C#N)=O)=O)NC(C(F)(F)F)=O

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(-20℃)

With Ice Pack

≥ 2 years