Nicotredole
CAS No. 29876-14-0
Nicotredole ( Tryptamide )
Catalog No. M28294 CAS No. 29876-14-0
Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 43 | Get Quote |
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5MG | 72 | Get Quote |
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10MG | 110 | Get Quote |
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25MG | 188 | Get Quote |
|
50MG | 295 | Get Quote |
|
100MG | 444 | Get Quote |
|
500MG | 963 | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameNicotredole
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NoteResearch use only, not for human use.
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Brief DescriptionNicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.
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DescriptionNicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.(In Vitro):Nicotredole inhibits prostaglandin synthetase activity in vitro . (In Vivo):Nicotredole produces antiinflammatory effects in carrageenin-induced rat paw oedema . Nicotredole reverses pyrogen-induced hyperthermia in rats, elicits analgesic effects in rats, prolongs the time of hexobarbital sleep in rats and inhibits locomotor activity in rats and mice . Nicotredole (i.p.) has LD50s of 1260 mg/kg and 1980 mg/kg for male rats and male mice, respectively . Nicotredole (p.o.) has LD50s of 8.5 g/kg and 9.3 g/kg for male rats and male mice, respectively . Nicotredole (25 mg/kg; p.o. or i.p.) undergoes fast absorption (t 1/2 =4.92-17.5 min) and elimination (t 1/2 =55.72-74.52 min), can reach C max (11-13 μg/cm 3 ) after 30 min, and gives AUC values in the range of 21.40-27.30 (μgh/cm 3 ) .
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SynonymsTryptamide
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number29876-14-0
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Formula Weight265.3
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Molecular FormulaC16H15N3O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCCc1c[nH]c2ccccc12)c1cccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Barlow RB, Burston KN. A comparison of cinobufotenine (the quaternary derivative of 5-HT) and some related compounds with coryneine (the quaternary derivative of dopamine) on the frog rectus, guinea-pig ileum and rat fundus strip preparations. Br J Pharmacol. 1980 Aug;69(4):597-600.
molnova catalog
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