Neotuberostemonine

CAS No. 143120-46-1

Neotuberostemonine( —— )

Catalog No. M19780 CAS No. 143120-46-1

Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 200 In Stock
10MG 295 In Stock
25MG 498 In Stock
50MG 710 In Stock
100MG 963 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Neotuberostemonine
  • Note
    Research use only, not for human use.
  • Brief Description
    Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
  • Description
    Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    143120-46-1
  • Formula Weight
    375.5
  • Molecular Formula
    C22H33NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC[C@H]1[C@H]2OC(=O)[C@@H](C)[C@H]2[C@@H]2C[C@@H]([C@@H]3C[C@H](C)C(=O)O3)N3CCCC[C@H]1[C@H]23
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xiang J Cheng S Feng T et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[J]. International Immunopharmacology 2016 36:158-164.
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