Neoandrographolide( Neoandrographolide )

Catalog No. M18343 CAS No. 27215-14-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Neoandrographolide
Note

Research use only, not for human use.
Brief Description

Neoandrographolide has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.
Description

Neoandrographolide is one of the principle diterpenoids isolated from A. paniculata, a well-recognized medicinal plant in Asia. Extracts from A. paniculata have been reported to exert a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities.
In Vitro

——
In Vivo

——
Synonyms

Neoandrographolide
Pathway

Others
Target

Other Targets
Recptor

COX-2| iNOS
Research Area

Others-Field
Indication

——

CAS Number

27215-14-1
Formula Weight

480.6
Molecular Formula

C26H40O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (208.08 mM)
SMILES

O1CC=C(C1=O)CC[C@@H]1C(=C)CC[C@@H]2[C@@](CCC[C@@]12C)(CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)C
Chemical Name

3-(2-((1R,4aS,5R,8aS)-5,8a-dimethyl-2-methylene-5-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)decahydronaphthalen-1-yl)ethyl)furan-2(5H)-one

1. Yang T,et al. Hypolipidemic effects of andrographolide and neoandrographolide in mice and rats. Phytother Res. 2013 Apr;27(4):618-23.

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