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Nemorubicin

CAS No. 108852-90-0

Nemorubicin ( Methoxymorpholinyldoxorubicin ,PNU 152243 ,PNU-152243A )

Catalog No. M22079 CAS No. 108852-90-0

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 177 In Stock
25MG 410 In Stock
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Biological Information

  • Product Name
    Nemorubicin
  • Note
    Research use only, not for human use.
  • Brief Description
    Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?
  • Description
    Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile.?The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives.
  • Synonyms
    Methoxymorpholinyldoxorubicin ,PNU 152243 ,PNU-152243A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    108852-90-0
  • Formula Weight
    643.64
  • Molecular Formula
    C32H37NO13
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:45 mg/mL (69.91 mM)
  • SMILES
    CO[C@@H]1CN(CCO1)[C@H]1C[C@H](O[C@H]2C[C@@](O)(Cc3c(O)c4C(=O)c5cccc(OC)c5C(=O)c4c(O)c23)C(=O)CO)O[C@@H](C)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Quintieri L, et al. In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes. Biochem Pharmacol. 2008 Sep 15;76(6):784-95.
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