Negletein
CAS No. 29550-13-8
Negletein ( Negletein )
Catalog No. M18382 CAS No. 29550-13-8
Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 249 | In Stock |
|
10MG | 426 | In Stock |
|
25MG | 683 | In Stock |
|
50MG | 888 | In Stock |
|
100MG | 1242 | In Stock |
|
500MG | 2511 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameNegletein
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NoteResearch use only, not for human use.
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Brief DescriptionNegletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.
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DescriptionNegletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows a comparable redox-active potential, and it (50μM, 4h) can activate Nrf2. Negletein shows significant antimicrobial activity. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. Negletein (IC50: 3.89 +/- 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.
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SynonymsNegletein
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number29550-13-8
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Formula Weight284.26
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Molecular FormulaC16H12O5
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Purity98%
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Solubility——
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SMILESCOC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)O
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Chemical Name4H-1-Benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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