Negletein

CAS No. 29550-13-8

Negletein ( Negletein )

Catalog No. M18382 CAS No. 29550-13-8

Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 249 In Stock
10MG 426 In Stock
25MG 683 In Stock
50MG 888 In Stock
100MG 1242 In Stock
500MG 2511 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Negletein
  • Note
    Research use only, not for human use.
  • Brief Description
    Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.
  • Description
    Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows a comparable redox-active potential, and it (50μM, 4h) can activate Nrf2. Negletein shows significant antimicrobial activity. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. Negletein (IC50: 3.89 +/- 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.
  • Synonyms
    Negletein
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    29550-13-8
  • Formula Weight
    284.26
  • Molecular Formula
    C16H12O5
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)O
  • Chemical Name
    4H-1-Benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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