Negletein
CAS No. 29550-13-8
Negletein ( Negletein )
Catalog No. M18382 CAS No. 29550-13-8
Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 249 | In Stock |
|
10MG | 426 | In Stock |
|
25MG | 683 | In Stock |
|
50MG | 888 | In Stock |
|
100MG | 1242 | In Stock |
|
500MG | 2511 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNegletein
-
NoteResearch use only, not for human use.
-
Brief DescriptionNegletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β.
-
DescriptionNegletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. Negletein shows a comparable redox-active potential, and it (50μM, 4h) can activate Nrf2. Negletein shows significant antimicrobial activity. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. Negletein (IC50: 3.89 +/- 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.
-
SynonymsNegletein
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number29550-13-8
-
Formula Weight284.26
-
Molecular FormulaC16H12O5
-
Purity98%
-
Solubility——
-
SMILESCOC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)O
-
Chemical Name4H-1-Benzopyran-4-one, 5,6-dihydroxy-7-methoxy-2-phenyl-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Sulfisomidine
Sulfisomidine is asulfonamide antibacterial.
-
ISOBUTYRALDEHYDE OXI...
2-methylpropanal oxime is an aldoxime derived from 2-methylpropanal. It derives from an isobutyraldehyde.
-
TMB dihydrochloride
TMB dihydrochloride is an enzyme-linked immunosorbent assays (ELISA) and an excellent colorimetric substrate for the detection of horseradish peroxidase (HRP)-labeled probes used in staining procedures immunohistochemistry.