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Negamycin

CAS No. 33404-78-3

Negamycin ( Negamycin )

Catalog No. M14133 CAS No. 33404-78-3

A dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Negamycin
  • Note
    Research use only, not for human use.
  • Brief Description
    A dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse.
  • Description
    A dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse; interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.
  • Synonyms
    Negamycin
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    33404-78-3
  • Formula Weight
    248.28
  • Molecular Formula
    C9H20N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)CN(C)NC(C[C@H](N)C[C@@H](O)CN)=O
  • Chemical Name
    N-((3R,5R)-3,6-diamino-5-hydroxyhexanamido)-N-methylglycine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Arakawa M, et al. J Biochem. 2003 Nov;134(5):751-8.
2. Polikanov YS, et al. Mol Cell. 2014 Nov 20;56(4):541-50.
3. Cocozaki AI, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8188-93.
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