Negamycin
CAS No. 33404-78-3
Negamycin( Negamycin )
Catalog No. M14133 CAS No. 33404-78-3
A dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 1773 | Get Quote |
|
50MG | 3582 | Get Quote |
|
100MG | 4950 | Get Quote |
|
200MG | Get Quote | Get Quote |
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500MG | Get Quote | Get Quote |
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1G | Get Quote | Get Quote |
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Biological Information
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Product NameNegamycin
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NoteResearch use only, not for human use.
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Brief DescriptionA dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse.
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DescriptionA dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse; interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.
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In Vitro——
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In Vivo——
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SynonymsNegamycin
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number33404-78-3
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Formula Weight248.283
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Molecular FormulaC9H20N4O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)CN(C)NC(C[C@H](N)C[C@@H](O)CN)=O
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Chemical NameN-((3R,5R)-3,6-diamino-5-hydroxyhexanamido)-N-methylglycine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Arakawa M, et al. J Biochem. 2003 Nov;134(5):751-8.
2. Polikanov YS, et al. Mol Cell. 2014 Nov 20;56(4):541-50.
3. Cocozaki AI, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8188-93.
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