Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - 5-HT Receptor - Naronapride

Naronapride

CAS No. 860174-12-5

Naronapride ( ATI-7505 )

Catalog No. M16233 CAS No. 860174-12-5

Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 682 Get Quote
50MG 2507 Get Quote
100MG 3168 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Naronapride
  • Note
    Research use only, not for human use.
  • Brief Description
    Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM.
  • Description
    Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM; displays negligible affinity for Kv11.1 channels (Ki=24,500 nM), and no effect on cardiac repolarization; shows potential for treatment of gastrointestinal motility disorders.Other Indication Phase 2 Clinical
  • Synonyms
    ATI-7505
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    860174-12-5
  • Formula Weight
    537.10
  • Molecular Formula
    C27H41ClN4O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O[C@H]1CN2CCC1CC2)CCCCCN3C[C@H](OC)[C@H](NC(C4=CC(Cl)=C(N)C=C4OC)=O)CC3
  • Chemical Name
    [(3R)-1-azabicyclo[2.2.2]octan-3-yl] 6-[(3S,4R)-4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-3-methoxypiperidin-1-yl]hexanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Manabe N, et al. Expert Opin Investig Drugs. 2010 Jun;19(6):765-75.
2. Bowersox SS, et al. Drug Metab Dispos. 2011 Jul;39(7):1170-80.
3. Hoffman JM, et al. Gastroenterology. 2012 Apr;142(4):844-854.e4.
4. Camilleri M, et al. Neurogastroenterol Motil. 2007 Jan;19(1):30-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AVN-101

    A higly potent, orally bioavailable, BBB permeable 5-HT7 receptor antagonist with Ki of 153 pM, with slightly lesser potency toward 5-HT6, 5-HT2A and 5HT-2C (Ki=1.2-2.0 nM).

  • Trazodone hydrochlor...

    Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

  • Lamotrigine

    Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder.

Sign In Join Free