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NXL101
CAS No. 904302-98-3
NXL101( NXL 101 )
Catalog No. M16502 CAS No. 904302-98-3
NXL101 is a novel quinoline bacterial DNA gyrase and topoisomerase IV inhibitor that shows potent activity against gram-positive bacteria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameNXL101
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NoteResearch use only, not for human use.
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Brief DescriptionNXL101 is a novel quinoline bacterial DNA gyrase and topoisomerase IV inhibitor that shows potent activity against gram-positive bacteria.
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DescriptionNXL101 is a novel quinoline bacterial DNA gyrase and topoisomerase IV inhibitor that shows potent activity against gram-positive bacteria, including methicillin- and fluoroquinolone-resistant strains; inhibits S. aureus DNA gyrase and topoisomerase IV with IC50 of 1.0 and 18 uM, respectively.Bacterial Infection Phase 1 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsNXL 101
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number904302-98-3
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Formula Weight504.635
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Molecular FormulaC25H29FN2O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C([C@H]1CN(CCSC2=CC=CS2)CC[C@H]1CC[C@@H](C3=C(F)C=NC4=CC=C(OC)C=C34)O)O
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Chemical Name(3R,4R)-4-[(3S)-3-(3-Fluoro-6-methoxy-4-quinolinyl)-3-hydroxypropyl]-1-[2-(2-thienylthio)ethyl]-3-piperidinecarboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Black MT, et al. Antimicrob Agents Chemother. 2008 Sep;52(9):3339-49.
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