NVP-ADW742

CAS No. 475489-15-7

NVP-ADW742 ( —— )

Catalog No. M14584 CAS No. 475489-15-7

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NVP-ADW742
  • Note
    Research use only, not for human use.
  • Brief Description
    NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
  • Description
    NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    IGF-1R
  • Recptor
    IGF-1R
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    475489-15-7
  • Formula Weight
    453.38
  • Molecular Formula
    C28H31N5O
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: > 10mM
  • SMILES
    NC1=NC=NC2=C1C(=CN2C1CC(CN2CCCC2)C1)C1=CC(OCC2=CC=CC=C2)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mitsiades CS, et al. Y Cell, 2004, 5(3), 221-230.
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