NSC622608

CAS No. 2593254-90-9

NSC622608 ( —— )

Catalog No. M28030 CAS No. 2593254-90-9

NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 80 Get Quote
10MG 140 Get Quote
25MG 282 Get Quote
50MG 425 Get Quote
100MG 610 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NSC622608
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.
  • Description
    NSC622608 is a small-molecule ligand for V-domain Ig suppressor of T-cell activation (VISTA) which is an immune checkpoint that affects the ability of T-cells to attack tumors.(In Vitro):NSC622608 blocked VISTA signaling in vitro, enhanced T-cell proliferation, and restored T-cell activation in the presence of VISTA-expressing cancer cell lines.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antifection;MMP;Leishmania tropica
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2593254-90-9
  • Formula Weight
    322.2
  • Molecular Formula
    C9H12BrN3OS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C)C(SS1)=NC1=NCC2=CC=CO2.[H]Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Olaf Kunert, et al. Antiplasmodial and leishmanicidal activity of biflavonoids from Indian Selaginella bryopteris. Phytochemistry Letters,2008,1(4):171-4.
molnova catalog
related products
  • Kurarinone

    Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses.?Kurarinone may ameliorate chronic inflammatory skin diseases through the suppression of pathogenic CD4(+) T-cell differentiation and the overall immune response.

  • Darutoside

    Darutoside can as an appropriate treatment for wounds.

  • Cholestyramine

    Cholestyramine, a bile acid-binding resin, inhibits intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.