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NSC45586

CAS No. 6300-44-3

NSC45586( —— )

Catalog No. M24634 CAS No. 6300-44-3

NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 55 In Stock
5MG 87 In Stock
10MG 129 In Stock
25MG 219 In Stock
50MG 327 In Stock
100MG 520 In Stock
500MG 1107 In Stock
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Biological Information

  • Product Name
    NSC45586
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
  • Description
    NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PHLPP1|PHLPP2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6300-44-3
  • Formula Weight
    413.4
  • Molecular Formula
    C20H18N6NaO3+
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:82 mg/mL;Water:Insoluble;Ethanol:Insoluble
  • SMILES
    CC1=CC(=C(C=C1N)N)N=NC2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jackson T C , Verrier J D , Drabek T , et al. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.[J]. Journal of Pharmacology and Experimental Therapeutics, 2013, 347(2):516-528.
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