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NSC348884

CAS No. 81624-55-7

NSC348884 ( NSC348884; NSC 348884; NSC-348884 )

Catalog No. M19138 CAS No. 81624-55-7

NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 32 In Stock
5MG 50 In Stock
10MG 87 In Stock
25MG 171 In Stock
50MG 281 In Stock
100MG 405 In Stock
500MG 888 In Stock
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Biological Information

  • Product Name
    NSC348884
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.
  • Description
    NSC348884 is a nucleophosmin inhibitor. NSC348884 also disrupts oligomer formation and induces apoptosis in human cancer cells.
  • Synonyms
    NSC348884; NSC 348884; NSC-348884
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    nucleophosmin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    81624-55-7
  • Formula Weight
    636.81
  • Molecular Formula
    C38H40N10
  • Purity
    98%
  • Solubility
    DMSO : ≥ 34 mg/mL; 53.39 mM
  • SMILES
    Cc1cc2c(cc1)nc(CN(CCN(Cc1nc3c([nH]1)cc(C)cc3)Cc1nc3c([nH]1)cc(C)cc3)Cc1nc3c([nH]1)cc(C)cc3)[nH]2
  • Chemical Name
    N,N,N',N'-tetrakis[(6-methyl-1H-benzimidazol-2-yl)methyl]ethane-1,2-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Qi W, et al. NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancercells. Oncogene. 2008 Jul 10;27(30):4210-20.
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