NS6180

CAS No. 353262-04-1

NS6180 ( NS6180; NS-6180; NS 6180 )

Catalog No. M14204 CAS No. 353262-04-1

NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 38 In Stock
5MG 58 In Stock
10MG 97 In Stock
25MG 212 In Stock
50MG 347 In Stock
100MG 516 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NS6180
  • Note
    Research use only, not for human use.
  • Brief Description
    NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.
  • Description
    NS6180 is a novel potent and selective KCa3.1 channel inhibitor(IC50= 9 nM) prevents T-cell activation and inflammation.
  • Synonyms
    NS6180; NS-6180; NS 6180
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    KCa3.1 channel
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    353262-04-1
  • Formula Weight
    323.33
  • Molecular Formula
    C16H12F3NOS
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 100 mM
  • SMILES
    O=C1CSC2=CC=CC=C2N1CC3=CC=CC(C(F)(F)F)=C3
  • Chemical Name
    4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Strobak D, et al. Br J Pharmacol. 2013 Jan;168(2):432-44.
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