NS-398

CAS No. 123653-11-2

NS-398 ( NS-398; NS 398; NS398 )

Catalog No. M10951 CAS No. 123653-11-2

COX-2 inhibitor and anti-inflammatory agent.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 27 In Stock
5MG 41 In Stock
10MG 55 In Stock
25MG 87 In Stock
50MG 168 In Stock
100MG 259 In Stock
200MG 337 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NS-398
  • Note
    Research use only, not for human use.
  • Brief Description
    COX-2 inhibitor and anti-inflammatory agent.
  • Description
    COX-2 inhibitor and anti-inflammatory agent.
  • Synonyms
    NS-398; NS 398; NS398
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-2
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    123653-11-2
  • Formula Weight
    314.36
  • Molecular Formula
    C13H18N2O5S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: > 10 mM
  • SMILES
    CS(=O)(NC1=CC=C([N+]([O-])=O)C=C1OC2CCCCC2)=O
  • Chemical Name
    N-[2-(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim J, et al. COX-2 inhibitor NS-398 suppresses doxorubicin-induced p53 accumulation through inhibition of ROS-mediated Jnk activation. Mol Carcinog. 2016 Jan 12. doi: 10.1002/mc.22458.
molnova catalog
related products
  • Emodin-8-glucoside

    Emodin-8-beta-D-glucoside functions to protect from focal cerebral injury induced by ischemia and reperfusion.

  • Ibuprofen

    A non-selective, reversible COX inhibitor with IC50 of 1 ug/mL and 46 ug/mL for COX-1 and COX-2 in enzyme assay, respectively.

  • Etoricoxib

    Etoricoxib(MK-0663) selectively inhibited COX-2 in human whole blood assays in vitro, with an IC50 value of 1.1 ± 0.1 μM for COX-2 (LPS-induced prostaglandin E2 synthesis), compared with an IC50 value of 116 ± 8 μM for COX-1 (serum thromboxane B2 generation after clotting of the blood).